Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7–mediated Vangl ubiquitination and endoplasmic reticulum–associated degradation
-
- Di Feng
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Jin Wang
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Wei Yang
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Jingyu Li
- Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR, China.
-
- Xiaochen Lin
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Fangzi Zha
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Xiaolu Wang
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Luyao Ma
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Nga Ting Choi
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Yusuke Mii
- Exploratory Research Center on Life and Living Systems (ExCELLS) and National Institute for Basic Biology, National Institutes of Natural Sciences, Okazaki, Japan.
-
- Shinji Takada
- Exploratory Research Center on Life and Living Systems (ExCELLS) and National Institute for Basic Biology, National Institutes of Natural Sciences, Okazaki, Japan.
-
- Michael S. Y. Huen
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
-
- Yusong Guo
- Division of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China.
-
- Liang Zhang
- Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR, China.
-
- Bo Gao
- School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Description
<jats:p>The abundance of core Wnt/PCP protein Vangl is regulated by the endoplasmic reticulum–associated degradation (ERAD) pathway.</jats:p>
Journal
-
- Science Advances
-
Science Advances 7 (20), 2021-05-14
American Association for the Advancement of Science (AAAS)
- Tweet
Details 詳細情報について
-
- CRID
- 1360857593681728768
-
- ISSN
- 23752548
-
- Data Source
-
- Crossref
- KAKEN