Observation of liquid–liquid phase separation of ataxin-3 and quantitative evaluation of its concentration in a single droplet using Raman microscopy

DOI Web Site 6 Citations 56 References Open Access

Abstract

<p>Liquid–liquid phase separation (LLPS) plays an important role in a variety of biological processes. We have established a method to quantify a single droplet formed by LLPS using the Raman band of water as an internal standard.</p>

Journal

  • Chemical Science

    Chemical Science 12 (21), 7411-7418, 2021

    Royal Society of Chemistry (RSC)

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