Intraneural perineuriomas: diagnostic value of magnetic resonance neurography
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- Luciana León Cejas
- Department of Neurology Británico Hospital Buenos Aires Argentina
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- Daniela Binaghi
- Department of Radiology Favaloro Foundation Buenos Aires Argentina
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- Mariano Socolovsky
- Department of Neurosurgery Británico Hospital Buenos Aires Argentina
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- Alberto Dubrovsky
- Department of Neurology Favaloro Foundation Buenos Aires Argentina
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- Laura Pirra
- Department of Neurology Favaloro Foundation Buenos Aires Argentina
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- Cintia Marchesoni
- Department of Neurology Británico Hospital Buenos Aires Argentina
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- Ana Pardal
- Department of Neurology Británico Hospital Buenos Aires Argentina
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- Soledad Monges
- Department of Neurology Garrahan Hospital Buenos Aires Argentina
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- Gabriela Peretti
- Department of Neurology Garrahan Hospital Buenos Aires Argentina
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- Ana L. Taratuto
- Garrahan Hospital Neuropathology Laboratory Buenos Aires Argentina
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- Fabiana Lubinieki
- Garrahan Hospital Neuropathology Laboratory Buenos Aires Argentina
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- Ricardo Reisin
- Department of Neurology Británico Hospital Buenos Aires Argentina
説明
<jats:title>Abstract</jats:title><jats:p>Intraneural perineurioma (IP) is an under‐recognized hypertrophic peripheral nerve tumor. It affects young patients involving frequently the sciatic nerve and its branches and presents with a progressive, painless and predominantly motor deficit. Magnetic resonance neurography (MRN) is a useful tool to localize the lesion, evaluate its extension, and discriminate between different etiologies. We reviewed the clinical records of 11 patients with pathologically confirm IP. Eight patients were males with mean age 19 years. Initial complains were unilateral steppage (seven patients), bilateral steppage (one patient), unilateral gastrocnemius wasting (one patient), unilateral thigh atrophy (one patient), and unilateral hand weakness (one patient). Nine patients had mild painless sensory loss. Examinations revealed involvement of sciatic nerve extending into the peroneal nerve (eight patients), posterior tibial nerve (one patient), radial nerve (one patient), and femoral nerve (one patient). MRN revealed enlargement of the affected nerve isointense on T1‐weighted, hyperintense on T2 fat‐saturated images, and with avid enhancement on post‐contrast imaging. In all patients, a nerve biopsy confirmed the diagnosis. MRN allows early and non‐invasive identification of this tumor and is a key tool providing localization and differential diagnosis in patients with slowly progressive focal neuropathies.</jats:p>
収録刊行物
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- Journal of the Peripheral Nervous System
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Journal of the Peripheral Nervous System 23 (1), 23-28, 2017-12-07
Wiley