Lewis acid-catalyzed double addition of indoles to ketones: synthesis of bis(indolyl)methanes with all-carbon quaternary centers

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<p>A boron or silicon Lewis acid-catalyzed synthesis of bis(indolyl)methanes with all-carbon quaternary centers, including a tetra-aryl carbon center, by the two-fold addition of indoles to a broad range of ketones has been developed.</p>

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