Effectiveness of Electroconvulsive Therapy and Associated Cognitive Change in Schizophrenia
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- Phern-Chern Tor
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Jiangbo Ying
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- New Fei Ho
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Mingyuan Wang
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Donel Martin
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Chai Pin Ang
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Chunzhen Tan
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Lee Shen Yap
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Vincent John Magat Lu
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Brett Simpson
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Yee Ming Mok
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
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- Colleen Loo
- From the *General Psychiatry, Institute of Mental Health, Buangkok View, Singapore; †Black Dog Institute, Randwick; ‡School of Psychiatry, University of New South Wales, Sydney; and §Older Adult Mental Health Service, St George Hospital, Kogarah, New South Wales, Australia.
書誌事項
- タイトル別名
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- A Naturalistic, Comparative Study of Treating Schizophrenia With Electroconvulsive Therapy
この論文をさがす
説明
<jats:sec> <jats:title>Objective</jats:title> <jats:p>There is limited evidence regarding the relative treatment effectiveness and cognitive effects of different types of electroconvulsive therapy (ECT) in schizophrenia. In this study, we sought to determine the overall effectiveness and compare the symptomatic and cognitive outcomes of patients with schizophrenia who received different modalities of ECT treatment.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>Patients received 1 of 4 of the following ECT modalities: bitemporal ECT with age-based dosing, right unilateral ECT with seizure threshold–based dosing, bitemporal ECT with seizure threshold–based dosing, and bifrontal ECT with seizure threshold–based dosing ECT. The Brief Psychiatric Rating Scale (BPRS) and Montreal Cognitive Assessment (MoCA) were administered to 62 patients before and after the ECT course.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>There was a significant improvement in both the total and psychotic subscales of BPRS and MoCA scores across the patients after the course of ECT. The global improvements in both BPRS and MoCA scores after ECT were not influenced by the type of ECT administered. Age-based dosing, however, was associated with poorer memory outcomes posttreatment. The overall symptomatic response rate, defined as 40% or more reduction in the psychotic subscale of BPRS, was 64.5%. The response rates did not significantly differ between the 4 types of ECT.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Our present findings suggest that an acute course of ECT is effective in schizophrenia and may have cognitive benefits for some patients.</jats:p> </jats:sec>
収録刊行物
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- The Journal of ECT
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The Journal of ECT 33 (4), 272-277, 2017-12
Ovid Technologies (Wolters Kluwer Health)