Global, Regional, and National Burden of Calcific Aortic Valve and Degenerative Mitral Valve Diseases, 1990–2017
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- Simon Yadgir
- Institute for Health Metrics and Evaluation (S.Y., C.O.J., C.M.B., S.I.H., A.H.M., M.R.N., G.A.R.), University of Washington, Seattle.
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- Catherine Owens Johnson
- Institute for Health Metrics and Evaluation (S.Y., C.O.J., C.M.B., S.I.H., A.H.M., M.R.N., G.A.R.), University of Washington, Seattle.
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- Victor Aboyans
- Department of Cardiology, Dupuytren University Hospital, Limoges, France (V. Aboyans).
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- Oladimeji M. Adebayo
- College of Medicine, University College Hospital, College of Medicine, University College Hospital, Ibadan, Oyo, Nigeria (O.M.A.).
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- Rufus Adesoji Adedoyin
- Department of Medical Rehabilitation, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria (R.A.A.).
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- Mohsen Afarideh
- Endocrinology and Metabolism Research Center (M.A., A.E.), Tehran University of Medical Sciences, Iran.
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- Fares Alahdab
- Evidence Based Practice Center, Mayo Clinic Foundation for Medical Education and Research, Rochester, MN (F.A.).
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- Alaa Alashi
- Department of Cardiovascular Medicine (A.A., M.M.G.), Cleveland Clinic, OH.
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- Vahid Alipour
- Health Management and Economics Research Center (V. Alipour, J.A., S.A., A. Rezapour), Iran University of Medical Sciences, Tehran.
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- Jalal Arabloo
- Health Management and Economics Research Center (V. Alipour, J.A., S.A., A. Rezapour), Iran University of Medical Sciences, Tehran.
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- Samad Azari
- Health Management and Economics Research Center (V. Alipour, J.A., S.A., A. Rezapour), Iran University of Medical Sciences, Tehran.
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- Celine M. Barthelemy
- Institute for Health Metrics and Evaluation (S.Y., C.O.J., C.M.B., S.I.H., A.H.M., M.R.N., G.A.R.), University of Washington, Seattle.
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- Catherine P. Benziger
- Heart and Vascular Center, Essentia Health, Duluth, MN (C.P.B.).
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- Adam E. Berman
- Department of Medicine, Medical College of Georgia at Augusta University (A.E.B.).
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- Ali Bijani
- Social Determinants of Health Research Center, Babol University of Medical Sciences, Mazandaran, Iran (A.B.).
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- Juan J. Carrero
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (J.J.C.).
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- Félix Carvalho
- Applied Molecular Biosciences Unit (F.C.), University of Porto, Portugal.
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- Andre R. Durães
- Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran (A.D.).
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- Alireza Esteghamati
- Endocrinology and Metabolism Research Center (M.A., A.E.), Tehran University of Medical Sciences, Iran.
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- Talha A. Farid
- Division of Cardiovascular Medicine, University of Louisville, KY (T.A.F., A.R.K.).
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- Farshad Farzadfar
- Non-communicable Diseases Research Center (F.F.), Tehran University of Medical Sciences, Iran.
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- Eduarda Fernandes
- REQUIMTE/LAQV (E.F.), University of Porto, Portugal.
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- Irina Filip
- Psychiatry Department, Kaiser Permanente, Fontana, CA (I.F.).
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- Mohamed M. Gad
- Department of Cardiovascular Medicine (A.A., M.M.G.), Cleveland Clinic, OH.
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- Samer Hamidi
- School of Health and Environmental Studies, Hamdan Bin Mohammed Smart University, Dubai, United Arab Emirates (S.H.).
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- Simon I. Hay
- Institute for Health Metrics and Evaluation (S.Y., C.O.J., C.M.B., S.I.H., A.H.M., M.R.N., G.A.R.), University of Washington, Seattle.
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- Olayinka Stephen Ilesanmi
- Department of Community Medicine, University of Ibadan, Nigeria (O.S.I.).
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- Seyed Sina Naghibi Irvani
- Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran (S.S.N.I.).
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- Mikk Jürisson
- Institute of Family Medicine and Public Health, University of Tartu, Tartumaa, Estonia (M.J.).
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- Amir Kasaeian
- Hematology-Oncology and Stem Cell Transplantation Research Center (A. Kasaeian), Tehran University of Medical Sciences, Iran.
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- Andre Pascal Kengne
- Non-communicable Diseases Research Unit, Medical Research Council South Africa, Cape Town (A.P.K.).
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- Abdur Rahman Khan
- Division of Cardiovascular Medicine, University of Louisville, KY (T.A.F., A.R.K.).
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- Adnan Kisa
- Department of Health Management and Health Economics, Kristiania University College, Oslo, Norway (A. Kisa).
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- Sezer Kisa
- Department of Nursing and Health Promotion, Oslo Metropolitan University, Norway (S.K.).
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- Dhaval Kolte
- Department of Medicine, Brown University, Providence, RI (D.K.).
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- Navid Manafi
- Ophthalmology Department (N.M.), Iran University of Medical Sciences, Tehran.
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- Amir Manafi
- Department of Surgery, University of Virginia, Charlottesville (A.M.).
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- George A. Mensah
- Department of Medicine, University of Cape Town, South Africa (A.P.K., G.A.M., K.S.).
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- Erkin M. Mirrakhimov
- Faculty of General Medicine, Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan (E.M.M.).
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- Yousef Mohammad
- Internal Medicine Department, King Saud University, Riyadh, Saudi Arabia (Y.M.).
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- Ali H. Mokdad
- Institute for Health Metrics and Evaluation (S.Y., C.O.J., C.M.B., S.I.H., A.H.M., M.R.N., G.A.R.), University of Washington, Seattle.
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- Ruxandra Irina Negoi
- Anatomy and Embryology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania (R.I.N.).
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- Huong Lan Thi Nguyen
- Institute for Global Health Innovations, Duy Tan University, Hanoi, Vietnam (H.L.T.N.).
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- Trang Huyen Nguyen
- Center of Excellence in Behavioral Health, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam (T.H.N.).
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- Molly R. Nixon
- Institute for Health Metrics and Evaluation (S.Y., C.O.J., C.M.B., S.I.H., A.H.M., M.R.N., G.A.R.), University of Washington, Seattle.
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- Catherine M. Otto
- Division of Cardiology (C.M.O., G.A.R.), University of Washington, Seattle.
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- Shanti Patel
- Department of Medicine, Maimonides Medical Center, Brooklyn, NY (S.P.).
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- Thomas Pilgrim
- Department of Cardiology, University of Bern, Switzerland (T.P.).
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- Amir Radfar
- College of Graduate Health Sciences, A.T. Still University, Mesa, AZ (A. Radfar).
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- David Laith Rawaf
- WHO Collaborating Centre for Public Health Education and Training (D.L.R.), Imperial College London, United Kingdom.
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- Salman Rawaf
- Department of Primary Care and Public Health (S.R.), Imperial College London, United Kingdom.
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- Wasiq Faraz Rawasia
- Cardiovascular Medicine, West Virginia University, Morgantown (W.F.R.).
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- Aziz Rezapour
- Health Management and Economics Research Center (V. Alipour, J.A., S.A., A. Rezapour), Iran University of Medical Sciences, Tehran.
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- Leonardo Roever
- Department of Clinical Research, Federal University of Uberl ândia, Brazil (L.R.).
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- Anas M. Saad
- Faculty of Medicine, Ain Shams University, Cairo, Egypt (A.M.S.).
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- Seyedmohammad Saadatagah
- Department of Cardiology (S. Saadatagah), Tehran University of Medical Sciences, Iran.
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- Subramanian Senthilkumaran
- Emergency Department, Manian Medical Centre, ERODE, Tamil Nadu, India (S. Senthilkumaran).
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- Karen Sliwa
- Department of Medicine, University of Cape Town, South Africa (A.P.K., G.A.M., K.S.).
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- Berhe Etsay Tesfay
- Department of Public Health, Adigrat University, Tigray, Ethiopia (B.E.T.).
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- Bach Xuan Tran
- Department of Health Economics, Hanoi Medical University, Vietnam (B.X.T.).
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- Irfan Ullah
- Gomal Center of Biochemistry and Biotechnology, Gomal University, Faisalabad, Pakistan (I.U.).
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- Muthiah Vaduganathan
- Heart and Vascular Center, Harvard University, Boston, MA (M.V.).
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- Tommi Juhani Vasankari
- UKK Institute, Tampere, Finland (T.J.V.).
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- Charles D.A. Wolfe
- School of Population Health & Environmental Sciences, King’s College London, United Kingdom (C.D.A.W.).
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- Naohiro Yonemoto
- Department of Psychopharmacology, National Center of Neurology and Psychiatry, Tokyo, Japan (N.Y.).
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- Gregory A. Roth
- Institute for Health Metrics and Evaluation (S.Y., C.O.J., C.M.B., S.I.H., A.H.M., M.R.N., G.A.R.), University of Washington, Seattle.
Abstract
<jats:sec> <jats:title>Background:</jats:title> <jats:p>Nonrheumatic valvular diseases are common; however, no studies have estimated their global or national burden. As part of the Global Burden of Disease Study 2017, mortality, prevalence, and disability-adjusted life-years (DALYs) for calcific aortic valve disease (CAVD), degenerative mitral valve disease, and other nonrheumatic valvular diseases were estimated for 195 countries and territories from 1990 to 2017.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods:</jats:title> <jats:p>Vital registration data, epidemiologic survey data, and administrative hospital data were used to estimate disease burden using the Global Burden of Disease Study modeling framework, which ensures comparability across locations. Geospatial statistical methods were used to estimate disease for all countries, because data on nonrheumatic valvular diseases are extremely limited for some regions of the world, such as Sub-Saharan Africa and South Asia. Results accounted for estimated level of disease severity as well as the estimated availability of valve repair or replacement procedures. DALYs and other measures of health-related burden were generated for both sexes and each 5-year age group, location, and year from 1990 to 2017.</jats:p> </jats:sec> <jats:sec> <jats:title>Results:</jats:title> <jats:p>Globally, CAVD and degenerative mitral valve disease caused 102 700 (95% uncertainty interval [UI], 82 700–107 900) and 35 700 (95% UI, 30 500–42 500) deaths, and 12.6 million (95% UI, 11.4 million–13.8 million) and 18.1 million (95% UI, 17.6 million–18.6 million) prevalent cases existed in 2017, respectively. A total of 2.5 million (95% UI, 2.3 million–2.8 million) DALYs were estimated as caused by nonrheumatic valvular diseases globally, representing 0.10% (95% UI, 0.09%–0.11%) of total lost health from all diseases in 2017. The number of DALYs increased for CAVD and degenerative mitral valve disease between 1990 and 2017 by 101% (95% UI, 79%–117%) and 35% (95% UI, 23%–47%), respectively. There is significant geographic variation in the prevalence, mortality rate, and overall burden of these diseases, with highest age-standardized DALY rates of CAVD estimated for high-income countries.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions:</jats:title> <jats:p>These global and national estimates demonstrate that CAVD and degenerative mitral valve disease are important causes of disease burden among older adults. Efforts to clarify modifiable risk factors and improve access to valve interventions are necessary if progress is to be made toward reducing, and eventually eliminating, the burden of these highly treatable diseases.</jats:p> </jats:sec>
Journal
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- Circulation
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Circulation 141 (21), 1670-1680, 2020-05-26
Ovid Technologies (Wolters Kluwer Health)
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Details 詳細情報について
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- CRID
- 1360861294744543360
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- ISSN
- 15244539
- 00097322
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- Data Source
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- Crossref