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SPONTANEOUS REGRESSION OF PRIMARY RENAL CELL CARCINOMA WITH INFERIOR VENA CAVAL TUMOR THROMBUS
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- K.O. KOBAYASHI
- From the Department of Urology, Oji General Hospital, Tomakomai, and Department of Urology and Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan
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- TAKASHI SATO
- From the Department of Urology, Oji General Hospital, Tomakomai, and Department of Urology and Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan
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- KEN-ICHI SUNAOSHI
- From the Department of Urology, Oji General Hospital, Tomakomai, and Department of Urology and Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan
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- ATSUSHI TAKAHASHI
- From the Department of Urology, Oji General Hospital, Tomakomai, and Department of Urology and Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan
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- MITSUHARU TAMAKAWA
- From the Department of Urology, Oji General Hospital, Tomakomai, and Department of Urology and Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan
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Description
A 51-year-old woman was referred to our hospital with a left renal mass in December 1998. Computerized tomography (CT) of the abdomen revealed a 5 cm. mass in the left kidney with a thrombus in the renal vein extending into the infrahepatic vena cava (fig. 1, a and b). Ultrasonography guided biopsy of the renal mass performed elsewhere revealed malignant cells. The mass and thrombus were enhanced by intravenous bolus injection of contrast medium. Magnetic resonance imaging (MRI) confirmed a left renal mass extending into the inferior vena cava through the left renal vein (fig. 1, c). All findings were diagnostic of left renal cell carcinoma associated with left renal vein and inferior vena caval invasion. Performance status was grade 4. Laboratory findings revealed anemia and increased serum C-reactive protein. Because of poor general condition, the patient was followed with no medical treatment for renal cell carcinoma. In December 2000 CT of the abdomen revealed that the primary tumor in the left kidney had regressed (fig. 2, a). The tumor was not enhanced by intravenous bolus injection of contrast medium. The left renal vein and inferior vena cava seemed to have a normal appearance, which indicated that the tumor thrombus had regressed (fig. 2, b). MRI also showed apparent primary tumor resolution and a normal blood stream in the left renal vein and inferior vena cava (fig. 2, c and d). All findings were diagnostic of spontaneous regression of the left renal cell carcinoma with a tumor thrombus in the renal vein extending into the inferior vena cava.
Journal
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- Journal of Urology
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Journal of Urology 167 (1), 242-243, 2002-01
Ovid Technologies (Wolters Kluwer Health)
