Two New Eremophilane‐Type Sesquiterpenoids from Japanese Liverwort <i>Bazzania japonica</i>

  • Ryosuke Fukada
    Faculty of Science and Technology Shizuoka Institute of Science and Technology 2200-2 Toyosawa, Fukuroi Shizuoka 437-8555 Japan
  • Jin Kawano
    Faculty of Science and Technology Shizuoka Institute of Science and Technology 2200-2 Toyosawa, Fukuroi Shizuoka 437-8555 Japan
  • Tomoki Tsuruta
    Department of Chemistry, Graduate School of Science Osaka Metropolitan University 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka 558-8585 Japan
  • Takuto Nonaka
    Faculty of Science and Technology Shizuoka Institute of Science and Technology 2200-2 Toyosawa, Fukuroi Shizuoka 437-8555 Japan
  • Kosuke Sato
    Faculty of Science and Technology Shizuoka Institute of Science and Technology 2200-2 Toyosawa, Fukuroi Shizuoka 437-8555 Japan
  • Susumu Miyajima
    Faculty of Science and Technology Shizuoka Institute of Science and Technology 2200-2 Toyosawa, Fukuroi Shizuoka 437-8555 Japan
  • Shinnosuke Ishigami
    The United Graduate School of Agricultural Sciences, Kagoshima University 1-21-24, Korimoto Kagoshima 890-0065 Japan
  • Takahiro Ishii
    The United Graduate School of Agricultural Sciences, Kagoshima University 1-21-24, Korimoto Kagoshima 890-0065 Japan
  • Keisuke Nishikawa
    Department of Chemistry, Graduate School of Science Osaka Metropolitan University 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka 558-8585 Japan
  • Yoshinori Asakawa
    Faculty of Pharmaceutical Sciences Tokushima Bunri University, Yamashiro-cho Tokushima 770-8514 Japan
  • Takashi Kamada
    Faculty of Science and Technology Shizuoka Institute of Science and Technology 2200-2 Toyosawa, Fukuroi Shizuoka 437-8555 Japan

Description

<jats:title>Abstract</jats:title><jats:p>Two new eremophilane‐type sesquiterpenoids, fusumaols A (<jats:bold>1</jats:bold>) and B (<jats:bold>2</jats:bold>), were isolated from the stem‐leafy liverwort, <jats:italic>Bazzania japonica</jats:italic> collected in Mori‐Machi, Shizuoka, Japan. Their structures were established using extensive spectroscopic (IR, MS, and 2D NMR) data, and the absolute configuration of <jats:bold>1</jats:bold> was determined by the modified Mosher's method. This is the first time eremophilanes have been discovered in the liverwort genus <jats:italic>Bazzania</jats:italic>. Compounds <jats:bold>1</jats:bold> and <jats:bold>2</jats:bold> were evaluated for their repellent activity against the adult population of the rice weevil <jats:italic>Sitophilus zeamais</jats:italic> using the modified filter paper impregnation method. Both sesquiterpenoids showed moderate repellent activities.</jats:p>

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