Inflammatory Bowel Diseases and Gut Microbiota

DOI Web Site 107 References Open Access
  • Yuri Haneishi
    Department of Applied Biological Science, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Fuchu-shi 183-8509, Tokyo, Japan
  • Yuma Furuya
    Department of Applied Biological Science, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Fuchu-shi 183-8509, Tokyo, Japan
  • Mayu Hasegawa
    Department of Applied Biological Science, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Fuchu-shi 183-8509, Tokyo, Japan
  • Antonio Picarelli
    Department of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy
  • Mauro Rossi
    Institute of Food Sciences, National Research Council (CNR), Via Roma 64, 83100 Avellino, Italy
  • Junki Miyamoto
    Department of Applied Biological Science, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Fuchu-shi 183-8509, Tokyo, Japan

Description

<jats:p>Inflammatory bowel disease (IBD) is an inflammatory disease of the gastrointestinal tract, the incidence of which has rapidly increased worldwide, especially in developing and Western countries. Recent research has suggested that genetic factors, the environment, microbiota, and immune responses are involved in the pathogenesis; however, the underlying causes of IBD are unclear. Recently, gut microbiota dysbiosis, especially a decrease in the abundance and diversity of specific genera, has been suggested as a trigger for IBD-initiating events. Improving the gut microbiota and identifying the specific bacterial species in IBD are essential for understanding the pathogenesis and treatment of IBD and autoimmune diseases. Here, we review the different aspects of the role played by gut microbiota in the pathogenesis of IBD and provide a theoretical basis for modulating gut microbiota through probiotics, fecal microbiota transplantation, and microbial metabolites.</jats:p>

Journal

References(107)*help

See more

Related Projects

See more

Details 詳細情報について

Report a problem

Back to top