Clinical practice guidelines and real-life practice in hepatocellular carcinoma: A Japanese perspective

DOI PDF Web Site 1 Citations 53 References Open Access

Abstract

<jats:p>Striking advances in systemic therapy for unresectable advanced hepatocellular carcinoma (HCC) have improved the average prognosis of patients with HCC. As a result, the guidelines for the treatment of HCC have changed significantly. However, various issues have emerged in clinical practice. First, there is no established biomarker that can predict response to systemic therapy. Second, there is no established treatment regimen after primary systemic therapy, including combined immunotherapy. Third, there is no established treatment regimen for intermediate-stage HCC. These points make the current guidelines ambiguous. In this review, we present the Japanese guidelines for the diagnosis and treatment of HCC based on the latest evidence; introduce various efforts mainly in Japanese real-life practice to update these guidelines; and present our perspectives on future guidelines.</jats:p>

Journal

Citations (1)*help

See more

References(53)*help

See more

Related Projects

See more

Details 詳細情報について

Report a problem

Back to top