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- Chiara Cavallini
- Institute of Clinical Physiology, National Research Council, via Giuseppe Moruzzi 1, 56124 Pisa, Italy
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- Giuseppe Vitiello
- Department of Chemical, Materials and Production Engineering (DICMaPI), University of Naples Federico II, Piazzale V. Tecchio 80, 80125 Napoli, Italy
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- Barbara Adinolfi
- Institute of Applied Physics “Nello Carrara”, National Research Council, via Madonna del Piano 10, 50019 Sesto Fiorentino, FI, Italy
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- Brigida Silvestri
- Department of Chemical, Materials and Production Engineering (DICMaPI), University of Naples Federico II, Piazzale V. Tecchio 80, 80125 Napoli, Italy
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- Paolo Armanetti
- Institute of Clinical Physiology, National Research Council, via Giuseppe Moruzzi 1, 56124 Pisa, Italy
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- Paola Manini
- Department of Chemical Sciences, University of Naples Federico II, via Cintia 21, I-80126 Napoli, Italy
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- Alessandro Pezzella
- Department of Chemical Sciences, University of Naples Federico II, via Cintia 21, I-80126 Napoli, Italy
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- Marco d’Ischia
- Department of Chemical Sciences, University of Naples Federico II, via Cintia 21, I-80126 Napoli, Italy
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- Giuseppina Luciani
- Department of Chemical, Materials and Production Engineering (DICMaPI), University of Naples Federico II, Piazzale V. Tecchio 80, 80125 Napoli, Italy
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- Luca Menichetti
- Institute of Clinical Physiology, National Research Council, via Giuseppe Moruzzi 1, 56124 Pisa, Italy
説明
<jats:p>Melanins are a group of dark insoluble pigments found widespread in nature. In mammals, the brown-black eumelanins and the reddish-yellow pheomelanins are the main determinants of skin, hair, and eye pigmentation and play a significant role in photoprotection as well as in many biological functions ensuring homeostasis. Due to their broad-spectrum light absorption, radical scavenging, electric conductivity, and paramagnetic behavior, eumelanins are widely studied in the biomedical field. The continuing advancements in the development of biomimetic design strategies offer novel opportunities toward specifically engineered multifunctional biomaterials for regenerative medicine. Melanin and melanin-like coatings have been shown to increase cell attachment and proliferation on different substrates and to promote and ameliorate skin, bone, and nerve defect healing in several in vivo models. Herein, the state of the art and future perspectives of melanins as promising bioinspired platforms for natural regeneration processes are highlighted and discussed.</jats:p>
収録刊行物
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- Nanomaterials
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Nanomaterials 10 (8), 1518-, 2020-08-03
MDPI AG