The CuAAC: Principles, Homogeneous and Heterogeneous Catalysts, and Novel Developments and Applications

  • Steve Neumann
    Institute of Chemistry, Chair of Macromolecular Chemistry Martin‐Luther University Halle‐Wittenberg von Danckelmannplatz 4 D‐06120 Halle (Saale) Germany
  • Michel Biewend
    Institute of Chemistry, Chair of Macromolecular Chemistry Martin‐Luther University Halle‐Wittenberg von Danckelmannplatz 4 D‐06120 Halle (Saale) Germany
  • Sravendra Rana
    School of Engineering University of Petroleum and Energy Studies (UPES) Dehradun Uttarakhand 248007 India
  • Wolfgang H. Binder
    Institute of Chemistry, Chair of Macromolecular Chemistry Martin‐Luther University Halle‐Wittenberg von Danckelmannplatz 4 D‐06120 Halle (Saale) Germany

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<jats:title>Abstract</jats:title><jats:p>The copper‐catalyzed azide/alkyne cycloaddition reaction (CuAAC) has emerged as the most useful “click” chemistry. Polymer science has profited enormously from CuAAC by its simplicity, ease, scope, applicability and efficiency. Basic principles of the CuAAC are reviewed with a focus on homogeneous and heterogeneous catalysts, ligands, anchimeric assistance, and basic chemical principles. Recent developments of ligand design and acceleration are discussed.</jats:p>

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