Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles

  • Charles A. Specht
    Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • E. Jane Homan
    ioGenetics LLC, Madison, Wisconsin, USA
  • Chrono K. Lee
    Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • Zhongming Mou
    Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • Christina L. Gomez
    Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • Maureen M. Hester
    Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • Ambily Abraham
    Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • Florentina Rus
    Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • Gary R. Ostroff
    Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA
  • Stuart M. Levitz
    Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

抄録

<jats:p>Cryptococcosis, due to infection by fungi of the<jats:named-content content-type="genus-species">Cryptococcus neoformans</jats:named-content>species complex, is responsible for substantial morbidity and mortality in immunocompromised persons, particularly those with AIDS. Cryptococcal vaccines are a public health priority yet are not available for human use.</jats:p>

収録刊行物

  • mBio

    mBio 13 (1), 2022-02-22

    American Society for Microbiology

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