Rotavirus NSP1 Contributes to Intestinal Viral Replication, Pathogenesis, and Transmission

DOI Web Site 1 Citations
  • Gaopeng Hou
    Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA
  • Qiru Zeng
    Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA
  • Jelle Matthijnssens
    KU Leuven-University of Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Leuven, Belgium
  • Harry B. Greenberg
    VA Palo Alto Health Care System, Department of Veterans Affairs, Palo Alto, California, USA
  • Siyuan Ding
    Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA
  • Xiang-Jin Meng
    editor

Abstract

<jats:p> Rotavirus remains one of the most important causes of severe diarrhea and dehydration in young children worldwide. Although NSP1 is dispensable for rotavirus replication in cell culture, its exact role in virus infection <jats:italic>in vivo</jats:italic> remains unclear. </jats:p>

Journal

  • mBio

    mBio 12 (6), 2021-12-21

    American Society for Microbiology

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