Rapid increase in Omicron infections in England during December 2021: REACT-1 study
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- Paul Elliott
- School of Public Health, Imperial College London, London, UK.
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- Barbara Bodinier
- School of Public Health, Imperial College London, London, UK.
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- Oliver Eales
- School of Public Health, Imperial College London, London, UK.
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- Haowei Wang
- School of Public Health, Imperial College London, London, UK.
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- David Haw
- School of Public Health, Imperial College London, London, UK.
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- Joshua Elliott
- Imperial College Healthcare NHS Trust, London, UK.
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- Matthew Whitaker
- School of Public Health, Imperial College London, London, UK.
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- Jakob Jonnerby
- School of Public Health, Imperial College London, London, UK.
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- David Tang
- School of Public Health, Imperial College London, London, UK.
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- Caroline E. Walters
- School of Public Health, Imperial College London, London, UK.
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- Christina Atchison
- School of Public Health, Imperial College London, London, UK.
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- Peter J. Diggle
- Health Data Research (HDR) UK, Imperial College London, London, UK.
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- Andrew J. Page
- Quadram Institute, Norwich, UK.
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- Alexander J. Trotter
- Quadram Institute, Norwich, UK.
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- Deborah Ashby
- School of Public Health, Imperial College London, London, UK.
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- Wendy Barclay
- Department of Infectious Disease, Imperial College London, London, UK.
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- Graham Taylor
- Department of Infectious Disease, Imperial College London, London, UK.
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- Helen Ward
- School of Public Health, Imperial College London, London, UK.
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- Ara Darzi
- Imperial College Healthcare NHS Trust, London, UK.
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- Graham S. Cooke
- Imperial College Healthcare NHS Trust, London, UK.
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- Marc Chadeau-Hyam
- School of Public Health, Imperial College London, London, UK.
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- Christl A. Donnelly
- School of Public Health, Imperial College London, London, UK.
説明
<jats:p>The unprecedented rise in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections during December 2021 was concurrent with rapid spread of the Omicron variant in England and globally. We analyzed the prevalence of SARS-CoV-2 and its dynamics in England from the end of November to mid-December 2021 among almost 100,000 participants in the REACT-1 study. Prevalence was high with rapid growth nationally and particularly in London during December 2021, with an increasing proportion of infections due to Omicron. We observed large decreases in swab positivity among mostly vaccinated older children (12 to 17 years) relative to unvaccinated younger children (5 to 11 years), and in adults who received a third (booster) vaccine dose versus two doses. Our results reinforce the importance of vaccination and booster campaigns, although additional measures have been needed to control the rapid growth of the Omicron variant.</jats:p>
収録刊行物
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- Science
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Science 375 (6587), 1406-1411, 2022-03-25
American Association for the Advancement of Science (AAAS)