The Efficacy and Adverse Events of Testosterone Replacement Therapy in Hypogonadal Men: A Systematic Review and Meta-Analysis of Randomized, Placebo-Controlled Trials

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  • Oscar J Ponce
    Evidence-Based Practice Center, Mayo Clinic, Rochester, Minnesota
  • Gabriela Spencer-Bonilla
    Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota
  • Neri Alvarez-Villalobos
    Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota
  • Valentina Serrano
    Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota
  • Naykky Singh-Ospina
    Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, Florida
  • Rene Rodriguez-Gutierrez
    Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota
  • Alejandro Salcido-Montenegro
    Universidad Autonoma de Nuevo Leon, Hospital Universitario “Dr. José E. Gonzalez,” Plataforma INVEST-KER Mexico, Monterrey, Nuevo León, México
  • Raed Benkhadra
    Evidence-Based Practice Center, Mayo Clinic, Rochester, Minnesota
  • Larry J Prokop
    Evidence-Based Practice Center, Mayo Clinic, Rochester, Minnesota
  • Shalender Bhasin
    Section of Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center for Function Promoting Therapies, Brigham and Women's Hospital-Harvard Medical School, Boston, Massachusetts
  • Juan P Brito
    Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota

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