Tumor microenvironment-regulated nanoplatforms for the inhibition of tumor growth and metastasis in chemo-immunotherapy
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- Xueping Yu
- Graduate School of Creative Science and Engineering, Waseda University, 3-4-1 Shin-Okubo, Shinjuku-ku, Tokyo 169-8555, Japan
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- Xiupeng Wang
- Health and Medical Research Institute, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
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- Atsushi Yamazaki
- Graduate School of Creative Science and Engineering, Waseda University, 3-4-1 Shin-Okubo, Shinjuku-ku, Tokyo 169-8555, Japan
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- Xia Li
- Health and Medical Research Institute, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
説明
<jats:p>Combining MM NPs with DOX and the anti-CTLA-4 antibody simultaneously inhibited the growth of primary tumors and distant untreated tumors owing to the optimized TME regulatory functions from different aspects.</jats:p>
収録刊行物
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- Journal of Materials Chemistry B
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Journal of Materials Chemistry B 10 (19), 3637-3647, 2022
Royal Society of Chemistry (RSC)