Investigating the interaction between dietary polyphenols, the SARS CoV-2 spike protein and the ACE-2 receptor

  • Dorothea Schmidt
    Department of Life Sciences and Chemistry, Jacobs University Bremen, Campusring 8, 28759 Bremen, Germany
  • Inamullah Hakeem Said
    Department of Life Sciences and Chemistry, Jacobs University Bremen, Campusring 8, 28759 Bremen, Germany
  • Nicholas Ohl
    Department of Life Sciences and Chemistry, Jacobs University Bremen, Campusring 8, 28759 Bremen, Germany
  • Mobinasaddat Sharifii
    Department of Life Sciences and Chemistry, Jacobs University Bremen, Campusring 8, 28759 Bremen, Germany
  • Paula Cotrell
    Department of Life Sciences and Chemistry, Jacobs University Bremen, Campusring 8, 28759 Bremen, Germany
  • Nikolai Kuhnert
    Department of Life Sciences and Chemistry, Jacobs University Bremen, Campusring 8, 28759 Bremen, Germany

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Description

<jats:p>In this contribution we show that 5-caffeoyl quinic acid reduces the affinity of the Coronavirus 2 Spike protein to the human ACE-2 receptor promising dietary prevention or slow-down of the SARS-CoC-2 pandemic.</jats:p>

Journal

  • Food & Function

    Food & Function 13 (15), 8038-8046, 2022

    Royal Society of Chemistry (RSC)

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