The Controversial Role of Adiponectin in Appetite Regulation of Animals

DOI Web Site 1 Citations
  • Ni Tang
    Department of Aquaculture, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 61000, China
  • Xin Zhang
    Department of Aquaculture, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 61000, China
  • Defang Chen
    Department of Aquaculture, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 61000, China
  • Zhiqiong Li
    Department of Aquaculture, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 61000, China

Description

<jats:p>Eating disorders and obesity are important health problems with a widespread global epidemic. Adiponectin (AdipoQ), the most abundant adipokine in the plasma, plays important roles in the regulation of energy homeostasis, glucose metabolism and lipid metabolism. Plasma adiponectin concentration is negatively associated with obesity and binge eating disorder. There is a growing interest in the appetite regulation function of adiponectin. However, the effect of AdipoQ on feeding behavior is controversial and closely related to nutritional status and food composition. In this review, we summarize the literatures about the discovery, structure, tissue distribution, receptors and regulation of nutritional status, and focus on the biological function of adiponectin in the regulation of food intake in the central and peripheral system.</jats:p>

Journal

  • Nutrients

    Nutrients 13 (10), 3387-, 2021-09-26

    MDPI AG

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