Fatal Arrhythmic Risks in Cardiac Sarcoidosis With Mildly Impaired Cardiac Function
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説明
The prognosis and later fatal arrhythmia in cardiac sarcoidosis (CS) with relatively preserved cardiac function were unclear.This study aimed to evaluate the prognosis and arrhythmic events in patients with CS and mildly impaired cardiac function.Data were collected from a nationwide Japanese cohort survey conducted in 57 hospitals (n = 420); 322 patients with CS with left ventricular ejection fraction (LVEF)35% were investigated.Ventricular tachycardia (VT) manifestation was present in 50 patients (16%) and absent in 272 (84%), of whom 36 (72%) and 46 (17%), respectively, had an implantable cardioverter-defibrillator (ICD). Over a median of 5 years, 23 all-cause deaths and 31 appropriate ICD discharges were observed. In Kaplan-Meier analysis, all-cause death did not differ between patients with and without VT manifestation (If concomitant NSVT with AVB, concomitant NSVT with abnormal Ga/PET, or abnormal Ga/PET is observed in patients with CS and mildly impaired cardiac function (LVEF35%), ICD should be considered as primary prevention.
収録刊行物
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- JACC: Asia
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JACC: Asia 3 (5), 755-763, 2023-10
Elsevier BV
