Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes
書誌事項
- 公開日
- 1998
- 権利情報
-
- https://www.karger.com/Services/SiteLicenses
- https://www.karger.com/Services/SiteLicenses
- DOI
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- 10.1159/000015032
- 公開者
- S. Karger AG
この論文をさがす
説明
<jats:p>We constructed a comparative cytogenetic map of 25 functional genes in mouse and rat X chromosomes by direct R-banding fluorescence in situ hybridization. Nineteen and 22 out of the 25 genes, which have been mapped on the human X chromosome, were newly localized to mouse and rat X chromosomes, respectively. Twenty-two additional genes were integrated in the rat-mouse-human comparative map of the X chromosome in this study. Comparison of the gene order indicated the presence of four chromosome segments with conserved linkage homology between mouse and rat X chromosomes, suggesting that a minimum of four chromosomal inversion events occurred between mouse and rat X chromosomes during the evolution of the two species. Four chromosome segments with conserved linkage homology were found between human and rat X chromosomes.</jats:p>
収録刊行物
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- Cytogenetic and Genome Research
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Cytogenetic and Genome Research 81 (3-4), 208-212, 1998
S. Karger AG