Dandruff is associated with the conjoined interactions between host and microorganisms
書誌事項
- 公開日
- 2016-05-12
- 権利情報
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- https://creativecommons.org/licenses/by/4.0
- https://creativecommons.org/licenses/by/4.0
- DOI
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- 10.1038/srep24877
- 公開者
- Springer Science and Business Media LLC
説明
<jats:title>Abstract</jats:title><jats:p>Dandruff is an unpleasant scalp disorder common to human populations. In this study, we systematically investigated the intra- and inter-associations among dandruff, physiological conditions such as sebum of the scalp, host demographics such as gender, age and the region of the scalp, and the microorganisms on the scalp. We found that the physiological conditions were highly relevant to the host age and varied in different regions of the same scalp. The sebum quantity and water content were negatively correlated with the formation of dandruff and had significant relationships with the two dominant but reciprocally inhibited bacteria on the scalp (<jats:italic>Propionibacterium</jats:italic> and <jats:italic>Staphylococcus</jats:italic>). The dominant fungus (<jats:italic>Malassezia</jats:italic> species) displayed contrary roles in its contribution to the healthy scalp micro-environment. Bacteria and fungi didn’t show a close association with each other, but the intramembers were tightly linked. Bacteria had a stronger relationship with the severity of dandruff than fungi. Our results indicated that the severity of dandruff was closely associated with the interactions between the host and microorganisms. This study suggests that adjusting the balance of the bacteria on the scalp, particularly by enhancing <jats:italic>Propionibacterium</jats:italic> and suppressing <jats:italic>Staphylococcus</jats:italic>, might be a potential solution to lessen dandruff.</jats:p>
収録刊行物
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- Scientific Reports
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Scientific Reports 6 (1), 24877-, 2016-05-12
Springer Science and Business Media LLC