<jats:sec sec-type="background"><jats:title>Background:</jats:title><jats:p>Despite the thermal challenge of demanding workloads performed in high cabin temperatures while wearing heavy heat-retardant clothing, information on physiological responses to racing V8 Supercars in hot conditions is not readily available.</jats:p></jats:sec><jats:sec sec-type="purpose"><jats:title>Purpose:</jats:title><jats:p>To describe the thermal, cardiovascular, and perceptual strain on V8 Supercar drivers competing in hot conditions.</jats:p></jats:sec><jats:sec sec-type="methods"><jats:title>Methods:</jats:title><jats:p>Thermal strain was indicated by body-core temperature using an ingested thermosensitive pill. Cardiovascular strain was assessed from heart rate, hydration status, and sweat rate. Perceptual strain was estimated from self-rated thermal sensation, thermal discomfort (modified Gagge scales), perceived exertion (Borg scale), and perceptual strain index.</jats:p></jats:sec><jats:sec sec-type="results"><jats:title>Results:</jats:title><jats:p>Prerace body-core temperatures were (mean ± SD) 37.7°C ± 0.4°C (range 37.0°C to 38.2°C), rising to 39.0°C ± 0.4°C (range 38.4°C to 39.7°C) postrace. Driver heart rates were >160 and >170 beats/min for 85.3% and 46.7% of racing, respectively. Sweat rates were 1.06 ± 0.12 L/h or 13.4 ± 1.2 mL · kg<jats:sup>−1</jats:sup> · h<jats:sup>−1</jats:sup>, and postrace dehydration was 0.6% ± 0.6% of prerace body mass. Drivers rated thermal sensation as hot (10.3 ± 0.9), thermal discomfort as uncomfortable (3.1 ± 1.0), and perceived exertion as very hard to very, very hard (8.7 ± 1.7) after the races. Overall physiological and perceptual strain were 7.4 ± 1.0 and 7.1 ± 1.2, respectively.</jats:p></jats:sec><jats:sec sec-type="conclusions"><jats:title>Conclusions:</jats:title><jats:p>Despite the use of cooling, V8 Supercar drivers endure thermal, cardiovascular, and perceptual strain during brief driving bouts in hot conditions.</jats:p></jats:sec>