Environmental Genome Shotgun Sequencing of the Sargasso Sea

DOI Web Site 被引用文献121件
  • J. Craig Venter
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Karin Remington
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • John F. Heidelberg
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Aaron L. Halpern
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Doug Rusch
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Jonathan A. Eisen
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Dongying Wu
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Ian Paulsen
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Karen E. Nelson
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • William Nelson
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Derrick E. Fouts
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Samuel Levy
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Anthony H. Knap
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Michael W. Lomas
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Ken Nealson
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Owen White
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Jeremy Peterson
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Jeff Hoffman
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Rachel Parsons
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Holly Baden-Tillson
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Cynthia Pfannkoch
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Yu-Hui Rogers
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.
  • Hamilton O. Smith
    The Institute for Biological Energy Alternatives, 1901 Research Boulevard, Rockville, MD 20850, USA.

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説明

<jats:p>We have applied “whole-genome shotgun sequencing” to microbial populations collected en masse on tangential flow and impact filters from seawater samples collected from the Sargasso Sea near Bermuda. A total of 1.045 billion base pairs of nonredundant sequence was generated, annotated, and analyzed to elucidate the gene content, diversity, and relative abundance of the organisms within these environmental samples. These data are estimated to derive from at least 1800 genomic species based on sequence relatedness, including 148 previously unknown bacterial phylotypes. We have identified over 1.2 million previously unknown genes represented in these samples, including more than 782 new rhodopsin-like photoreceptors. Variation in species present and stoichiometry suggests substantial oceanic microbial diversity.</jats:p>

収録刊行物

  • Science

    Science 304 (5667), 66-74, 2004-04-02

    American Association for the Advancement of Science (AAAS)

被引用文献 (121)*注記

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