NAD <sup>+</sup> repletion improves muscle function in muscular dystrophy and counters global PARylation

DOI Web Site 3 Citations
  • Dongryeol Ryu
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Hongbo Zhang
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Eduardo R. Ropelle
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Vincenzo Sorrentino
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Davi A. G. Mázala
    Department of Kinesiology, School of Public Health, University of Maryland, College Park, MD 20742, USA.
  • Laurent Mouchiroud
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Philip L. Marshall
    Interdisciplinary School of Health Sciences, University of Ottawa Brain and Mind Research Institute and Centre for Neuromuscular Disease, Ottawa, Ontario K1H 8M5, Canada.
  • Matthew D. Campbell
    Department of Radiology, University of Washington, Seattle, WA 98195, USA.
  • Amir Safi Ali
    Department of Radiology, University of Washington, Seattle, WA 98195, USA.
  • Gary M. Knowels
    Department of Radiology, University of Washington, Seattle, WA 98195, USA.
  • Stéphanie Bellemin
    Centre de Génétique et de Physiologie Moléculaires et Cellulaires, Université Claude Bernard Lyon 1, CNRS UMR 5534, 69622 Villeurbanne, France.
  • Shama R. Iyer
    Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Xu Wang
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Karim Gariani
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Anthony A. Sauve
    Department of Pharmacology, Weill Cornell Medical School, New York, NY 10065, USA.
  • Carles Cantó
    Nestlé Institute of Health Sciences, 1015 Lausanne, Switzerland.
  • Kevin E. Conley
    Department of Radiology, University of Washington, Seattle, WA 98195, USA.
  • Ludivine Walter
    Centre de Génétique et de Physiologie Moléculaires et Cellulaires, Université Claude Bernard Lyon 1, CNRS UMR 5534, 69622 Villeurbanne, France.
  • Richard M. Lovering
    Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Eva R. Chin
    Department of Kinesiology, School of Public Health, University of Maryland, College Park, MD 20742, USA.
  • Bernard J. Jasmin
    Department of Cellular and Molecular Medicine and Centre for Neuromuscular Disease, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
  • David J. Marcinek
    Department of Radiology, University of Washington, Seattle, WA 98195, USA.
  • Keir J. Menzies
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Johan Auwerx
    Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

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<jats:p> NAD <jats:sup>+</jats:sup> treatment can reverse the functional decline in degenerating muscles. </jats:p>

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