Detection rate of <sup>99m</sup>Tc‐MIBI single photon emission computed tomography (SPECT)/CT in preoperative planning for patients with primary hyperparathyroidism: A meta‐analysis
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- Giorgio Treglia
- Department of Nuclear Medicine PET/CT and Thyroid Center, Oncology Institute of Southern Switzerland Bellinzona Switzerland
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- Ramin Sadeghi
- Nuclear Medicine Research Center, Mashhad University of Medical Sciences Mashhad Iran
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- Camilla Schalin–Jäntti
- Division of Endocrinology Abdominal Center, University of Helsinki and Helsinki University Central Hospital Helsinki Finland
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- Carmelo Caldarella
- Institute of Nuclear Medicine, Catholic University Rome Italy
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- Luca Ceriani
- Department of Nuclear Medicine PET/CT and Thyroid Center, Oncology Institute of Southern Switzerland Bellinzona Switzerland
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- Luca Giovanella
- Department of Nuclear Medicine PET/CT and Thyroid Center, Oncology Institute of Southern Switzerland Bellinzona Switzerland
説明
<jats:title>abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Parathyroid scintigraphy using <jats:sup>99m</jats:sup>Tc‐MIBI single photon emission computed tomography (SPECT)/CT has been proposed as one of the most accurate localization techniques in patients with primary hyperparathyroidism (PHPT). The purpose of this review was to meta‐analyze published data on the detection rate of <jats:sup>99m</jats:sup>Tc‐MIBI SPECT/CT in the preoperative planning of patients with PHPT.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>A comprehensive literature search of studies published through June 2014 was performed. The pooled detection rate of this scintigraphic method including 95% confidence intervals (95% CIs) was calculated on a per patient‐based and on a per lesion‐based analysis by using a random effects model.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Twenty‐three articles including 1236 patients with PHPT were selected. The pooled detection rate of <jats:sup>99m</jats:sup>Tc‐MIBI SPECT/CT in the preoperative planning of patients with PHPT was 88% (95% CI = 84% to 92%) and 88% (95% CI = 82% to 92%) on a per patient‐based and per lesion‐based analysis, respectively.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>The <jats:sup>99m</jats:sup>Tc‐MIBI SPECT/CT has high detection rate for hyperfunctioning parathyroid glands in patients with PHPT. © 2015 Wiley Periodicals, Inc. <jats:italic>Head Neck</jats:italic> <jats:bold>38</jats:bold>: E2159–E2172, 2016</jats:p></jats:sec>
収録刊行物
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- Head & Neck
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Head & Neck 38 (S1), E2159-, 2015-07-06
Wiley
