Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of <scp>GPP</scp>

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  • Hideki Fujita
    Division of Dermatological Science Department of Dermatology Nihon University School of Medicine Tokyo Japan
  • Tadashi Terui
    Division of Dermatological Science Department of Dermatology Nihon University School of Medicine Tokyo Japan
  • Koremasa Hayama
    Division of Dermatological Science Department of Dermatology Nihon University School of Medicine Tokyo Japan
  • Masashi Akiyama
    Department of Dermatology Nagoya University Graduate School of Medicine Nagoya Japan
  • Shigaku Ikeda
    Department of Dermatology Juntendo University Faculty of Medicine Tokyo Japan
  • Tomotaka Mabuchi
    Department of Dermatology Tokai University School of Medicine Isehara Japan
  • Akira Ozawa
    Department of Dermatology Tokai University School of Medicine Isehara Japan
  • Takuro Kanekura
    Department of Dermatology Kagoshima University School of Medicine Kagoshima Japan
  • Michiko Kurosawa
    Department of Epidemiology and Environmental Health Juntendo University Faculty of Medicine Tokyo Japan
  • Mayumi Komine
    Department of Dermatology Jichi Medical University Shimotsuke Japan
  • Kimiko Nakajima
    Department of Dermatology Kochi Medical School Kochi University Nankoku Japan
  • Shigetoshi Sano
    Department of Dermatology Kochi Medical School Kochi University Nankoku Japan
  • Osamu Nemoto
    Kojinkai Sapporo Skin Clinic Sapporo Japan
  • Masahiko Muto
    Department of Dermatology Yamaguchi University School of Medicine Ube Japan
  • Yasutomo Imai
    Department of Dermatology Hyogo College of Medicine Nishinomiya Japan
  • Kiyofumi Yamanishi
    Department of Dermatology Hyogo College of Medicine Nishinomiya Japan
  • Yumi Aoyama
    Department of Dermatology Kawasaki Medical School Kurashiki Japan
  • Keiji Iwatsuki
    Department of Dermatology Dentistry and Pharmaceutical Sciences Okayama University Graduate School of Medicine Okayama Japan

説明

<jats:title>Abstract</jats:title><jats:p>Generalized pustular psoriasis (<jats:styled-content style="fixed-case">GPP</jats:styled-content>) is a rare disease characterized by recurrent fever and systemic flushing accompanied by extensive sterile pustules. The committee of the guidelines was founded as a collaborative project between the Japanese Dermatological Association and the Study Group for Rare Intractable Skin Diseases under the Ministry of Health, Labour, and Welfare Research Project on Overcoming Intractable Diseases. The aim of the guidelines was to provide current information to aid in the treatment of patients with <jats:styled-content style="fixed-case">GPP</jats:styled-content> in Japan. Its contents include the diagnostic and severity classification criteria for <jats:styled-content style="fixed-case">GPP</jats:styled-content>, its pathogenesis, and recommendations for the treatment of <jats:styled-content style="fixed-case">GPP</jats:styled-content>. Since there are few clinical trial data with high levels of evidence for this rare disease, recommendations by the committee are described in the present guidelines.</jats:p>

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