Translational frameshifting in the control of transposition in bacteria

Michael Chandler, Olivier Fayet

doi:10.1111/j.1365-2958.1993.tb01140.x

Translational frameshifting in the control of transposition in bacteria

DOI Web Site Web Site 被引用文献9件

書誌事項

公開日: 1993-02

権利情報

http://onlinelibrary.wiley.com/termsAndConditions#vor

DOI

10.1111/j.1365-2958.1993.tb01140.x

公開者: Wiley

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説明

<jats:title>Summary</jats:title><jats:p>The expression of an increasing number of genes of both prokaryotic and eukaryotic origin has been shown to be regulated at the translational level by programmed (sequence‐specific) ribosomal frame‐shifting. Among these are the bacterial insertion sequences IS<jats:italic>1</jats:italic> and two members of the widely distributed IS<jats:italic>3</jats:italic>‐family, IS<jats:italic>150</jats:italic> and IS<jats:italic>911.</jats:italic> Frameshifting provides a means of specifying several proteins with different functions using a minimum of genetic information. In this review, we survey present understanding of the way in which frameshifting is integrated into the overall control of transposition activity in these elements.</jats:p>