Optimal Prosthetic Graft Design for Small Diameter Vascular Grafts
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- Toshiya Nishibe
- *Department of Surgery, Fujita Health University, Toyoake, Japan; †Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT.
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- Yuka Kondo
- *Department of Surgery, Fujita Health University, Toyoake, Japan; †Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT.
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- Akihito Muto
- *Department of Surgery, Fujita Health University, Toyoake, Japan; †Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT.
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- Alan Dardik
- *Department of Surgery, Fujita Health University, Toyoake, Japan; †Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT.
説明
<jats:p> Autogenous vein and arterial grafts, such as great saphenous veins and internal mammary and radial arteries, remain the gold standard conduits for vascular reconstruction. Expanded polytetrafluoroethylene (PTFE) grafts, which exhibit little inflammatory and thrombogenic reactivity, are the most commonly used material of choice for small diameter vascular grafts when autogenous grafts are not available. Several modifications of the basic graft have been attempted to enhance graft healing of expanded PTFE grafts, and little but definite experimental and clinical improvement has been achieved so far. The technique of vascular tissue engineering, in combination with stem cell research, may hold the key for the creation of a practical and successful small diameter prosthetic graft. </jats:p>
収録刊行物
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- Vascular
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Vascular 15 (6), 356-360, 2007-12-01
SAGE Publications
