Diagnosis of Hepatitis A Virus Infection: a Molecular Approach

DOI Web Site 被引用文献3件
  • Omana V. Nainan
    Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333
  • Guoliang Xia
    Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333
  • Gilberto Vaughan
    Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333
  • Harold S. Margolis
    Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333

書誌事項

公開日
2006-01
権利情報
  • https://journals.asm.org/non-commercial-tdm-license
DOI
  • 10.1128/cmr.19.1.63-79.2006
公開者
American Society for Microbiology

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説明

<jats:sec><jats:title>SUMMARY</jats:title><jats:p>Current serologic tests provide the foundation for diagnosis of hepatitis A and hepatitis A virus (HAV) infection. Recent advances in methods to identify and characterize nucleic acid markers of viral infections have provided the foundation for the field of molecular epidemiology and increased our knowledge of the molecular biology and epidemiology of HAV. Although HAV is primarily shed in feces, there is a strong viremic phase during infection which has allowed easy access to virus isolates and the use of molecular markers to determine their genetic relatedness. Molecular epidemiologic studies have provided new information on the types and extent of HAV infection and transmission in the United States. In addition, these new diagnostic methods have provided tools for the rapid detection of food-borne HAV transmission and identification of the potential source of the food contamination.</jats:p></jats:sec>

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