<i>Porphyromonas gingivalis</i> Minor Fimbriae Are Required for Cell-Cell Interactions

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  • Xinghua Lin
    School of Dentistry, Meharry Medical College, Nashville, Tennessee
  • Jie Wu
    School of Dentistry, Meharry Medical College, Nashville, Tennessee
  • Hua Xie
    School of Dentistry, Meharry Medical College, Nashville, Tennessee

Abstract

<jats:title>ABSTRACT</jats:title> <jats:p> Two distinctive types of fimbriae have been identified in <jats:italic>Porphyromonas gingivalis</jats:italic> . In this report, we demonstrate that minor fimbriae are involved in <jats:italic>P. gingivalis</jats:italic> autoaggregation and colonization. A mutant with a deficiency in minor fimbriae can bind to a saliva-coated surface but does not form microcolonies as the wild-type strain does. </jats:p>

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