Advances in understanding – genetic basis of intellectual disability
Description
<ns4:p>Intellectual disability is the most common developmental disorder characterized by a congenital limitation in intellectual functioning and adaptive behavior. It often co-occurs with other mental conditions like attention deficit/hyperactivity disorder and autism spectrum disorder, and can be part of a malformation syndrome that affects other organs. Considering the heterogeneity of its causes (environmental and genetic), its frequency worldwide varies greatly. This review focuses on known genes underlying (syndromic and non-syndromic) intellectual disability, it provides a succinct analysis of their Gene Ontology, and it suggests the use of transcriptional profiling for the prioritization of candidate genes.</ns4:p>
Journal
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- F1000Research
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F1000Research 5 599-, 2016-04-07
F1000 Research Ltd
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Details 詳細情報について
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- CRID
- 1361137046085531904
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- ISSN
- 20461402
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- Data Source
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- Crossref