A clinical update on tuberous sclerosis complex‐associated neuropsychiatric disorders (TAND)
-
- Petrus J. de Vries
- Division of Child and Adolescent Psychiatry University of Cape Town Cape Town South Africa
-
- Lucy Wilde
- Cerebra Centre for Neurodevelopmental Disorders, School of Psychology University of Birmingham Birmingham United Kingdom
-
- Magdalena C. de Vries
- Division of Child and Adolescent Psychiatry University of Cape Town Cape Town South Africa
-
- Romina Moavero
- Child Neurology and Psychiatry Unit, Systems Medicine Department University of Rome Tor Vergata Rome Italy
-
- Deborah A. Pearson
- Department of Psychiatry & Behavioral Sciences, McGovern Medical School University of Texas Health Centre Houston Texas
-
- Paolo Curatolo
- Child Neurology and Psychiatry Unit, Systems Medicine Department University of Rome Tor Vergata Rome Italy
説明
<jats:title>Abstract</jats:title><jats:p>Tuberous sclerosis complex (TSC) is associated with a wide range of behavioral, psychiatric, intellectual, academic, neuropsychological, and psychosocial difficulties, which are often underdiagnosed and undertreated. Here, we present a clinical update on TSC‐associated neuropsychiatric disorders, abbreviated as “TAND,” to guide screening, diagnosis, and treatment in practice. The review is aimed at clinical geneticists, genetic counselors, pediatricians, and all generalists involved in the assessment and treatment of children, adolescents and adults with TSC, and related disorders. The review starts with a summary of the construct and levels of TAND, before presenting up‐to‐date information about each level of investigation. The review concludes with a synopsis of current and future TAND research.</jats:p>
収録刊行物
-
- American Journal of Medical Genetics Part C: Seminars in Medical Genetics
-
American Journal of Medical Genetics Part C: Seminars in Medical Genetics 178 (3), 309-320, 2018-08-16
Wiley