Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis

書誌事項

公開日
2002-04
権利情報
  • https://www.elsevier.com/tdm/userlicense/1.0/
  • https://www.elsevier.com/legal/tdmrep-license
DOI
  • 10.1016/s0140-6736(02)08359-9
公開者
Elsevier BV

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説明

Sclerosing pancreatitis is associated with raised concentrations of IgG4. We treated 22 patients with sclerosing pancreatitis, and identified and followed-up three with concomitant hydronephrosis caused by ureteral mass, later diagnosed as retroperitoneal fibrosis. We histologically examined the ureteral and pancreatic lesions of these patients and noted abundant infiltration of IgG4-bearing plasma cells in both tissues. Treatment with corticosteroids lowered serum concentrations of IgG4. IgG4 might also have a pathological role in a systemic fibrosing process that includes pancreatic and retroperitoneal lesions.

収録刊行物

  • The Lancet

    The Lancet 359 (9315), 1403-1404, 2002-04

    Elsevier BV

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