The GenomeAsia 100K Project enables genetic discoveries across Asia

DOI HANDLE PDF Web Site PubMed 研究データあり 被引用文献11件 参考文献69件 オープンアクセス

書誌事項

公開日
2019-12-04
資源種別
journal article
権利情報
  • https://creativecommons.org/licenses/by/4.0
  • https://creativecommons.org/licenses/by/4.0
DOI
  • 10.1038/s41586-019-1793-z
公開者
Springer Science and Business Media LLC

この論文をさがす

説明

<jats:title>Abstract</jats:title><jats:p>The underrepresentation of non-Europeans in human genetic studies so far has limited the diversity of individuals in genomic datasets and led to reduced medical relevance for a large proportion of the world’s population. Population-specific reference genome datasets as well as genome-wide association studies in diverse populations are needed to address this issue. Here we describe the pilot phase of the GenomeAsia 100K Project. This includes a whole-genome sequencing reference dataset from 1,739 individuals of 219 population groups and 64 countries across Asia. We catalogue genetic variation, population structure, disease associations and founder effects. We also explore the use of this dataset in imputation, to facilitate genetic studies in populations across Asia and worldwide.</jats:p>

収録刊行物

  • Nature

    Nature 576 (7785), 106-111, 2019-12-04

    Springer Science and Business Media LLC

被引用文献 (11)*注記

もっと見る

参考文献 (69)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ