Tick Repellents for Human Use: Prevention of Tick Bites and Tick-Borne Diseases

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書誌事項

公開日
2014-02
権利情報
  • https://journals.sagepub.com/page/policies/text-and-data-mining-license
DOI
  • 10.1089/vbz.2013.1410
公開者
SAGE Publications

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説明

<jats:p> Ticks are arthropods and the most important vectors of major human diseases after mosquitoes. Due to their impact on public health, <jats:italic toggle="yes">in vitro</jats:italic> and <jats:italic toggle="yes">in vivo</jats:italic> assays have been developed to identify molecules with repellent activities on ticks. Repellents are useful to reduce tick bite exposure and the potential transmission of pathogens; they can be used topically or in impregnated clothing. Presently, mainly synthetic molecules are commercialized as skin repellents, <jats:italic toggle="yes">e.g</jats:italic> ., <jats:italic toggle="yes">N</jats:italic> , <jats:italic toggle="yes">N</jats:italic> -diethyl-meta-toluamide (DEET), IR3535, picaridin or KBR 3023, and <jats:italic toggle="yes">para</jats:italic> -menthanediol. Permethrin is largely used for fabric impregnation. Intensive research has been conducted to identify new molecules with repellent activity and more recently, plant-derived molecules, as an alternative to synthetic molecules. </jats:p>

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