Relationship of Echocardiographic <i>Z</i> Scores Adjusted for Body Surface Area to Age, Sex, Race, and Ethnicity
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- Leo Lopez
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Steven Colan
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Mario Stylianou
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Suzanne Granger
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Felicia Trachtenberg
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Peter Frommelt
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Gail Pearson
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Joseph Camarda
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- James Cnota
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Meryl Cohen
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Andreea Dragulescu
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Michele Frommelt
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Olukayode Garuba
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Tiffanie Johnson
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Wyman Lai
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Joseph Mahgerefteh
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Ricardo Pignatelli
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Ashwin Prakash
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Ritu Sachdeva
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Brian Soriano
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Jonathan Soslow
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Christopher Spurney
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Shubhika Srivastava
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Carolyn Taylor
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Poonam Thankavel
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- Mary van der Velde
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
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- LuAnn Minich
- From the Nicklaus Children’s Hospital, Miami, FL (L.L.); Boston Children’s Hospital, MA (S.C., A.P.); National Heart, Lung, and Blood Institute, Bethesda, MD (M.S., G.P.); New England Research Institutes, Watertown, MA (S.G., F.T.); Children’s Hospital of Wisconsin, Milwaukee (P.F., M.F.); Ann & Robert Lurie Children’s Hospital, Chicago, IL (J. Camarda); Cincinnati Children’s Hospital Medical Center, OH (J. Cnota); Children’s Hospital of Philadelphia, PA (M.C.); Hospital for Sick Children,...
書誌事項
- タイトル別名
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- The Pediatric Heart Network Normal Echocardiogram Database
- 公開日
- 2017-11
- DOI
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- 10.1161/circimaging.117.006979
- 公開者
- Ovid Technologies (Wolters Kluwer Health)
この論文をさがす
説明
<jats:sec> <jats:title>Background—</jats:title> <jats:p> Published nomograms of pediatric echocardiographic measurements are limited by insufficient sample size to assess the effects of age, sex, race, and ethnicity. Variable methodologies have resulted in a wide range of <jats:italic>Z</jats:italic> scores for a single measurement. This multicenter study sought to determine <jats:italic>Z</jats:italic> scores for common measurements adjusted for body surface area (BSA) and stratified by age, sex, race, and ethnicity. </jats:p> </jats:sec> <jats:sec> <jats:title>Methods and Results—</jats:title> <jats:p> Data collected from healthy nonobese children ≤18 years of age at 19 centers with a normal echocardiogram included age, sex, race, ethnicity, height, weight, echocardiographic images, and measurements performed at the Core Laboratory. <jats:italic>Z</jats:italic> score models involved indexed parameters (X/BSA <jats:sup>α</jats:sup> ) that were normally distributed without residual dependence on BSA. The models were tested for the effects of age, sex, race, and ethnicity. Raw measurements from models with and without these effects were compared, and <5% difference was considered clinically insignificant because interobserver variability for echocardiographic measurements are reported as ≥5% difference. Of the 3566 subjects, 90% had measurable images. Appropriate BSA transformations (BSA <jats:sup>α</jats:sup> ) were selected for each measurement. Multivariable regression revealed statistically significant effects by age, sex, race, and ethnicity for all outcomes, but all effects were clinically insignificant based on comparisons of models with and without the effects, resulting in <jats:italic>Z</jats:italic> scores independent of age, sex, race, and ethnicity for each measurement. </jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions—</jats:title> <jats:p> Echocardiographic <jats:italic>Z</jats:italic> scores based on BSA were derived from a large, diverse, and healthy North American population. Age, sex, race, and ethnicity have small effects on the <jats:italic>Z</jats:italic> scores that are statistically significant but not clinically important. </jats:p> </jats:sec>
収録刊行物
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- Circulation: Cardiovascular Imaging
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Circulation: Cardiovascular Imaging 10 (11), e006979-, 2017-11
Ovid Technologies (Wolters Kluwer Health)
