Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking

  • S. A. Walsh
    Department of Dermatology, King’s College Hospital, Denmark Hill, London, UK
  • D. Creamer
    Department of Dermatology, King’s College Hospital, Denmark Hill, London, UK

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<jats:title>Abstract</jats:title> <jats:p>Summary Drug reaction with eosinophilia and systemic symptoms (DRESS) describes a severe medication-induced adverse reaction, which has cutaneous, haematological and solid-organ features. It is one of the triad of life-threatening drug hypersensitivity dermatoses, along with acute generalized exanthematous pustulosis (AGEP) and Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). In this article, we discuss several controversies that surround DRESS, including problems with nomenclature and the lack of consensus in diagnostic criteria.</jats:p>

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