Familial predisposition to uterine leiomyomas

E.M. Vikhlyaeva, Z.S. Khodzhaeva, N.D. Fantschenko

doi:10.1016/0020-7292(95)02533-i

Familial predisposition to uterine leiomyomas

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書誌事項

公開日: 1995-11

権利情報

http://onlinelibrary.wiley.com/termsAndConditions#vor

DOI

10.1016/0020-7292(95)02533-i

公開者: Wiley

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説明

<jats:title>Abstract</jats:title><jats:sec><jats:label/><jats:p>Objective: To study the clinical risk for gynecological disorders in first‐degree relatives in families with uterine leiomyoma. Method: Ninety‐seven families (215 female patients) were enrolled in this study; 97 patients and 118 of their near family relatives were examined. Results: Leiomyoma was discovered in 24.7% of cases, 2.2 times more frequently (P < 0.001) among the first‐degree female relatives in families with two or more verified leiomyoma cases. The rate of PCO disease was about 15% for both groups. Conclusion: These results confirm the concept of distinct predisposition to uterine leiomyoma and the PCO disease in first‐degree relatives in families with leiomyoma accumulation.</jats:p></jats:sec>