Vitamin <scp>D</scp> and multiple sclerosis in <scp>A</scp>sians and <scp>C</scp>aucasians: environmental and genetic aspects

書誌事項

公開日
2013-11-28
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/cen3.12058
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>Several genetic and environmental factors are thought to be associated with an increased risk of multiple sclerosis (<jats:styled-content style="fixed-case">MS</jats:styled-content>), the influence of which can differ between ethnicities. One of the most important risk factors for <jats:styled-content style="fixed-case">MS</jats:styled-content> is low serum levels of vitamin <jats:styled-content style="fixed-case">D</jats:styled-content>, and these levels also differ between ethnicities, probably mainly because of differences in skin pigmentation. Furthermore, genetic influences in vitamin <jats:styled-content style="fixed-case">D</jats:styled-content>‐related genes might also vary between ethnicities, reflecting different genetic backgrounds. The present review article discusses the association between vitamin <jats:styled-content style="fixed-case">D</jats:styled-content> and <jats:styled-content style="fixed-case">MS</jats:styled-content>, with a focus on Asians and Caucasians.</jats:p>

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