Phytotherapeutics in cancer invasion and metastasis

DOI Web Site Web Site 被引用文献1件
  • Bahare Salehi
    Medical Ethics and Law Research Center Shahid Beheshti University of Medical Sciences Tehran Iran
  • Paolo Zucca
    Department of Biomedical Sciences University of Cagliari Cagliari Italy
  • Mehdi Sharifi‐Rad
    Department of Medical Parasitology Zabol University of Medical Sciences Zabol 61663‐335 Iran
  • Raffaele Pezzani
    OU Endocrinology, Dept. Medicine (DIMED) University of Padova via Ospedale 105 Padova 35128 Italy
  • Sadegh Rajabi
    Department of Clinical Biochemistry, School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran
  • William N. Setzer
    Department of Chemistry University of Alabama in Huntsville Huntsville AL 35899 USA
  • Elena Maria Varoni
    Department of Biomedical, Surgical and Dental Sciences Milan State University Milan Italy
  • Marcello Iriti
    Department of Agricultural and Environmental Sciences Milan State University Milan Italy
  • Farzad Kobarfard
    Phytochemistry Research Center Shahid Beheshti University of Medical Sciences Tehran Iran
  • Javad Sharifi‐Rad
    Phytochemistry Research Center Shahid Beheshti University of Medical Sciences Tehran Iran

書誌事項

公開日
2018-04-19
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/ptr.6087
公開者
Wiley

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説明

<jats:p>Cancer is a multifactorial disease, and therefore, a multitarget approach is needed to face the complex cancer biology, based on the combined use of different natural and synthetic anticancer agents able to target synergistically multiple signaling pathways involved in carcinogenesis, including angiogenesis and metastasis. In this view, the plant kingdom represents an unlimited source of phytotherapeutics with promising perspectives in the field of anticancer drug discovery. This narrative review aims to provide an updated overview on the bioactive phytochemicals exhibiting a promising potential as adjuvants in conventional anticancer therapies, with emphasis on antiangiogenic and antimetastatic activities.</jats:p>

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