-
- Evangelia Lekka
- Department of Chemistry and Applied Biosciences Institute of Pharmaceutical Sciences ETH Zürich Switzerland
-
- Jonathan Hall
- Department of Chemistry and Applied Biosciences Institute of Pharmaceutical Sciences ETH Zürich Switzerland
説明
<jats:p>Noncoding <jats:styled-content style="fixed-case">RNA</jats:styled-content>s are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding <jats:styled-content style="fixed-case">RNA</jats:styled-content> expression and human diseases. These associations have been extensively reviewed, often with the focus on a particular microRNA (mi<jats:styled-content style="fixed-case">RNA</jats:styled-content>) (family) or a selected disease/pathology. In this Mini‐Review, we highlight a selection of studies in order to demonstrate the wide‐scale involvement of mi<jats:styled-content style="fixed-case">RNA</jats:styled-content>s and long noncoding <jats:styled-content style="fixed-case">RNA</jats:styled-content>s in the pathophysiology of three types of diseases: cancer, cardiovascular and neurological disorders. This research is opening new avenues to novel therapeutic approaches.</jats:p>
収録刊行物
-
- FEBS Letters
-
FEBS Letters 592 (17), 2884-2900, 2018-07-20
Wiley