Transient hypoparathyroidism following thyroidectomy: A prospective study and multivariate analysis of 604 consecutive patients

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  • Ottavio Cavicchi
    Department of ENT Endocrinology S. Orsola‐Malpighi Hospital Bologna University Bologna Italy
  • Ottavio Piccin
    Department of ENT Endocrinology S. Orsola‐Malpighi Hospital Bologna University Bologna Italy
  • Umberto Caliceti
    Department of ENT Endocrinology S. Orsola‐Malpighi Hospital Bologna University Bologna Italy
  • Angelo De Cataldis
    Department of General Surgery, Endocrinology S. Orsola‐Malpighi Hospital Bologna University Bologna Italy
  • Renato Pasquali
    Department of ENT Endocrinology S. Orsola‐Malpighi Hospital Bologna University Bologna Italy
  • Alberto Rinaldi Ceroni
    Department of ENT Endocrinology S. Orsola‐Malpighi Hospital Bologna University Bologna Italy

Abstract

<jats:sec><jats:title>Objectives</jats:title><jats:p>The purpose of this study was to identify the risk factors for postoperative transient hypoparathyroidism in a group of patients undergoing thyroid surgery.</jats:p></jats:sec><jats:sec><jats:title>Study Design</jats:title><jats:p>A prospective study was conducted on 604 patients undergoing thyroid surgery.</jats:p></jats:sec><jats:sec><jats:title>Subjects and Methods</jats:title><jats:p>Gender, final diagnosis, extent of resection, biology of pathology, intrathoracic involvement, surgery for recurrent multinodular goiter, and presence and number of parathyroid glands in a surgical specimen were analyzed as risk factors for postoperative transient hypoparathyroidism. The chi‐square test and a logistic regression analysis were applied. RESULTS: On logistic regression analysis, only the extent of surgery constituted an independent variable for transient hypoparathyroidism (<jats:italic>P</jats:italic> = 0.001).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>The extent of surgery to central and/or lateral neck lymph nodes is responsible for a high rate of transient hypoparathyroidism owing to a high probability of unplanned parathyroidectomy or parathyroid gland devascularization.</jats:p></jats:sec>

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