Recent Advances in Transition-Metal-Catalyzed Synthetic Transformations of Organosilicon Reagents
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- Takeshi Komiyama
- Department of Applied Chemistry, Chuo University, Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan
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- Yasunori Minami
- Research and Development Initiative, Chuo University, Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan
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- Tamejiro Hiyama
- Research and Development Initiative, Chuo University, Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan
書誌事項
- 公開日
- 2016-12-20
- DOI
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- 10.1021/acscatal.6b02374
- 公開者
- American Chemical Society (ACS)
この論文をさがす
説明
Organosilicon compounds act as a nucleophile upon activation by an appropriate base and behave in a manner similar to main-group organometallic reagents. In the last decades, structurally divergent organosilicon reagents are available and have become more employed for synthetic transformation with the aid of transition-metal complexes, because organosilicon compounds are in general superior to other organometallic compounds in view of stability, solubility, nontoxicity, and easy-handling. Particularly, cross-coupling of organosilicon reagents with organic halides or pseudohalides has been considered to be a useful tool for constructing the carbon frameworks of various target molecules such as pharmaceuticals and π-conjugated functional materials. Perfluoroalkylsilicon compounds such as CF3SiEt3 have found use as reagents for the metal-catalyzed introduction of perfluoroalkyl groups into many substrates. In addition, functionalized organosilicon reagents are readily accessible by catalytic approach startin...
収録刊行物
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- ACS Catalysis
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ACS Catalysis 7 (1), 631-651, 2016-12-20
American Chemical Society (ACS)