Clinical practice guidelines for the management of atopic dermatitis 2018

  • Norito Katoh
    Department of Dermatology Kyoto Prefectural University of Medicine Graduate School of Medical Science Kyoto Japan
  • Yukihiro Ohya
    Allergy Center National Center for Child Health and Development Tokyo Japan
  • Masanori Ikeda
    Department of Pediatric Acute Medicine Okayama University Graduate School of Medicine, Dentistry, and Pharmacuetical Sciences Okayama Japan
  • Tamotsu Ebihara
    Department of Dermatology Keio University School of Medicine Tokyo Japan
  • Ichiro Katayama
    Department of Dermatology Graduate School of Medicine Osaka University Suita Japan
  • Hidehisa Saeki
    Department of Dermatology Graduate School of Medicine Nihon Medical School Tokyo Japan
  • Naoki Shimojo
    Department of Pediatrics Graduate School of medicine Chiba University Chiba Japan
  • Akio Tanaka
    Department of Dermatology Hiroshima University Graduate School of Biomedical Sciences Hiroshima Japan
  • Takeshi Nakahara
    Division of Skin Surface Sensing Department of Dermatology Graduate School of Medical Sciences Kyushu University Fukuoka Japan
  • Mizuho Nagao
    Division of Clinical Research National Hospital Organization Mie National Hospital Tsu Japan
  • Michihiro Hide
    Department of Dermatology Hiroshima University Graduate School of Biomedical Sciences Hiroshima Japan
  • Yuji Fujita
    Department of Pediatrics Graduate School of medicine Chiba University Chiba Japan
  • Takao Fujisawa
    Division of Allergy National Hospital Organization Mie National Hospital Tsu Japan
  • Masaki Futamura
    Division of Pediatrics National Hospital Organization Nagoya Medical Center Nagoya Japan
  • Koji Masuda
    Department of Dermatology Kyoto Prefectural University of Medicine Graduate School of Medical Science Kyoto Japan
  • Hiroyuki Murota
    Department of Dermatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Kiwako Yamamoto‐Hanada
    Allergy Center National Center for Child Health and Development Tokyo Japan

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Abstract

<jats:title>Abstract</jats:title><jats:p>Atopic dermatitis (<jats:styled-content style="fixed-case">AD</jats:styled-content>) is a disease characterized by relapsing eczema with pruritus as a primary lesion. The current strategies to treat <jats:styled-content style="fixed-case">AD</jats:styled-content> in Japan from the perspective of evidence‐based medicine consist of three primary measures: (i) the use of topical corticosteroids and tacrolimus ointment as the main treatment for the inflammation; (ii) topical application of emollients to treat the cutaneous barrier dysfunction; and (iii) avoidance of apparent exacerbating factors, psychological counseling and advice about daily life. The guidelines present recommendations to review clinical research articles, evaluate the balance between the advantages and disadvantages of medical activities, and optimize medical activity‐related patient outcomes with respect to several important points requiring decision‐making in clinical practice.</jats:p>

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