書誌事項
- 公開日
- 1997-04
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/mrm.1910370427
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>In fMRI, images can be collected in a very short time; therefore, high temporal resolution is possible in principle. However, the temporal resolution is limited by a blurred intrinsic hemodynamic response and a finite signal‐to‐noise ratio. To determine the upper limit of temporal resolution in a single area during repeated tasks, motor cortex activity was investigated during visually instructed finger movements. <jats:italic>Without averaging</jats:italic>, a sequence of four single‐finger movements with an execution time of approximately 2 s can be resolved when the delay time between consecutive sequences is at least 3 s. The hemodynamic response time is constant for each subject, but not among different subjects. The temporal resolution can be better when the signal from spatially distinct regions is examined. For a series of experiments involving a visually instructed <jats:italic>delayed</jats:italic> cued finger movement task with a well‐defined, independently determined, variable delay time, time courses in the motor area are distinct from each other in two experiments if the difference in delay time is as little as 2 s. The activation in the visual area due to the presentation of the task serves here as an internal time reference. By comparing a set of fMRI time courses in multiple distinct areas, serial neural processing may be investigated.</jats:p>
収録刊行物
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- Magnetic Resonance in Medicine
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Magnetic Resonance in Medicine 37 (4), 631-636, 1997-04
Wiley