Subcellular distribution of tetrodotoxin in puffer fish liver

DOI Web Site Web Site PubMed 被引用文献7件

書誌事項

公開日
1999-12
権利情報
  • https://www.elsevier.com/tdm/userlicense/1.0/
  • https://www.elsevier.com/legal/tdmrep-license
DOI
  • 10.1016/s0041-0101(99)00100-2
公開者
Elsevier BV

この論文をさがす

説明

The liver homogenate of puffer fish was fractionated into blood cell, nuclear, mitochondrial, microsomal and cytosol fractions by the differential centrifugation method. All the five fractions were toxic to mice, although the toxin amount was significantly high in the cytosol fraction. Analyses by HPLC and LC-FABMS demonstrated that tetrodotoxin is the major toxic principle in each fraction. These results reveal that tetrodotoxin is widely distributed in organelles in liver cells, though predominantly in the cytosol fraction.

収録刊行物

  • Toxicon

    Toxicon 37 (12), 1833-1837, 1999-12

    Elsevier BV

被引用文献 (7)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ