Non-viral nanocarriers for intracellular delivery of microRNA therapeutics

  • Zhiman Bai
    School of Physics and Materials Science
  • Jing Wei
    Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)
  • Changmin Yu
    Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)
  • Xisi Han
    Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)
  • Xiaofei Qin
    Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)
  • Chengwu Zhang
    Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)
  • Wenzhen Liao
    Department of Nutrition and Food Hygiene
  • Lin Li
    Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)
  • Wei Huang
    Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)

説明

<p>MicroRNAs are small regulatory noncoding RNAs that regulate various biological processes. Herein, we will present the development of the strategies for intracellular miRNAs delivery, and specially focus on the rational designed routes, their mechanisms of action, as well as potential therapeutics used in the host cells or<italic>in vivo</italic>studies.</p>

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