Intermolecular Hydroacylation by Transition‐Metal Complexes

DOI Web Site Web Site Web Site 11 Citations

Description

<jats:title>Abstract</jats:title><jats:p>In this review, transition‐metal‐catalyzed intermolecular hydroacylation, which is a direct synthetic protocol generating ketones from aldehydes and unsaturated hydrocarbons, will be discussed. In order to avoid decarbonylation, one of the major side‐reactions occurring in transition‐metal‐catalyzed hydroacylation, several important strategies have been developed: An aldehyde ligand bearing a coordinating heteroatom at an appropriate position, a chelation auxiliary, and a masked form of the aldehyde, such as an aldimine or allylamine. Hydroacylation or its variations can also be applied to the synthesis of cycloalkanones and an α,β‐unsaturated ketone or to the carbon–carbon triple bond cleavage of an alkyne.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)</jats:p>

Journal

Citations (11)*help

See more

Report a problem

Back to top