β-Lactam Antibiotics Form Distinct Haptenic Structures on Albumin and Activate Drug-Specific T-Lymphocyte Responses in Multiallergic Patients with Cystic Fibrosis

  • Rosalind E. Jenkins
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • Fiazia S. Yaseen
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • Manal M. Monshi
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • Paul Whitaker
    Regional Adult Cystic Fibrosis Unit, St. James’s Hospital, Leeds, England
  • Xiaoli Meng
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • John Farrell
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • Jane Hamlett
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • Joseph P. Sanderson
    Adaptimmune Limited, 57 Jubilee Avenue, Milton Park, Abingdon, Oxfordshire, OX14 4RX, England
  • Sabah El-Ghaiesh
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • Daniel Peckham
    Regional Adult Cystic Fibrosis Unit, St. James’s Hospital, Leeds, England
  • Munir Pirmohamed
    The Wolfson Centre for Personalised Medicine, Department of Pharmacology, The University of Liverpool, 1-5 Brownlow Street, Liverpool L69 3GL, England
  • B. Kevin Park
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England
  • Dean J. Naisbitt
    MRC Centre for Drug Safety Science, Department of Pharmacology, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, England

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